کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2963710 | 1178572 | 2009 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis](/preview/png/2963710.png)
SummaryTherapeutic angiogenesis is an important means for salvaging tissues from severe ischemic diseases in patients with no option for other vascular interventions. A number of recent studies examined the possibilities of cell transplantation-mediated angiogenesis using autologous bone marrow mononuclear cells, CD34+ cells, peripheral mononuclear cells, etc. Subcutaneous adipose tissue can be harvested by relatively easy technology. Recent studies indicate that adipose tissue contains progenitor cells that can give rise to several mesenchymal lineages. Moreover, these progenitor cells can release multiple angiogenic growth factors including vascular endothelial growth factor, hypatocyte growth factor, and chemokine stromal cell-derived factor. The combination of these biological properties of adipose-derived regenerative cells indicates that autologous adipose tissue will be a useful cell source for therapeutic angiogenesis.
Journal: Journal of Cardiology - Volume 53, Issue 2, April 2009, Pages 155–163