کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2968834 1178888 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tp-e/QT ratio as an index of arrhythmogenesis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Tp-e/QT ratio as an index of arrhythmogenesis
چکیده انگلیسی

An increasing number of basic and clinical studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and that amplification of the Tp-e interval is associated with malignant ventricular arrhythmias. In this review, we outline the utility of the Tp-e interval and the Tp-e/QT ratio as an electrocardiographic index of arrhythmogenesis for both congenital and acquired ion channel disease leading to ventricular arrhythmias. In healthy individuals, the Tp-e/QT ratio has a mean value of approximately 0.21 in the precordial leads and it remains relatively constant between the heart rates from 60 to 100 beats per minute. Interestingly, the Tp-e/QT ratio is significantly greater in the patients at risk for arrhythmic event such as those with long QT syndrome, Brugada syndrome, short QT syndrome, and also in patients with organic heart disease such as acute myocardial infarction. Functional reentry is the underlying mechanism for arrhythmogenesis associated with an increased Tp-e/QT ratio.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electrocardiology - Volume 41, Issue 6, November–December 2008, Pages 567–574
نویسندگان
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