کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2999968 | 1180312 | 2009 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A Comparison of Long- and Short-Acting Opioids for the Treatment of Chronic Noncancer Pain: Tailoring Therapy to Meet Patient Needs
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کلمات کلیدی
PHNADLNSAIDATCTCASAOLBPQOLExtended-releaseSNRIBPIQuality of life - کیفیت زندگیSustained-release - آزادی دائمیadverse effect - اثر نامطلوبnonsteroidal anti-inflammatory drug - داروهای ضد التهابی غیر استروئیدیTricyclic antidepressant - داروهای ضدافسردگی سه حلقه ایchronic noncancer pain - درد مزمن غیرانسانیActivities of daily living - فعالیت های روزمره زندگیbrief pain inventory - فهرست کم دردImmediate-release - فوری آزادیLAO - لاوserotonin norepinephrine reuptake inhibitor - مهارکننده بازجذب سروتونین نوراپی نفرینpostherpetic neuralgia - نورالژی پسرشپتیکdiabetic neuropathy - نوروپاتی دیابتیLow back pain - کمر دردControlled-release - کنترل آزاد
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A Comparison of Long- and Short-Acting Opioids for the Treatment of Chronic Noncancer Pain: Tailoring Therapy to Meet Patient Needs A Comparison of Long- and Short-Acting Opioids for the Treatment of Chronic Noncancer Pain: Tailoring Therapy to Meet Patient Needs](/preview/png/2999968.png)
چکیده انگلیسی
Management of chronic noncancer pain (CNCP) requires a comprehensive assessment of the patient, the institution of a structured treatment regimen, an ongoing reassessment of the painful condition and its response to therapy, and a continual appraisal of the patient's adherence to treatment. For many patients with CNCP, the analgesic regimen will include opioids. Physicians should consider the available evidence of efficacy, the routes of administration, and the pharmacokinetics and pharmacodynamics of the various formulations as they relate to the temporal characteristics of the patient's pain. When making initial decisions, physicians should decide whether to prescribe a short-acting opioid (SAO) with a relatively quick onset of action and short duration of analgesic activity, a long-acting opioid (LAO) with a longer duration of analgesic action but a potentially longer onset of action, or both. Studies suggest that SAOs and LAOs are both effective for most types of CNCP. A review of published studies found no data to suggest that either SAOs or LAOs are generally more efficacious for treating any particular CNCP condition. The LAOs may provide more stable analgesia with less frequent dosing; however, opioid therapy should be tailored to the pain state and the individual patient, and SAOs may be appropriate for some patients with CNCP. MEDLINE and PubMed searches were conducted to locate relevant studies published from January 1975 to April 2008 using the following search terms: opioids, short-acting opioids, long-acting opioids, chronic pain, chronic pain AND opioids, and narcotics. English-only randomized controlled trials and nonrandomized studies were considered.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 84, Issue 7, July 2009, Pages 602-612
Journal: Mayo Clinic Proceedings - Volume 84, Issue 7, July 2009, Pages 602-612
نویسندگان
Charles E. MD, Daniel I. MD,