Remitting Seronegative Symmetrical Synovitis With Pitting Edema Syndrome in a Rural Tertiary Care Practice: A Retrospective Analysis

Our population of patients with RS3PE is similar to those documented in previous reports: elderly, predominantly male, and responsive to corticosteroids. However, our series is clinically differentiated by a greater use of adjunctive disease-modifying antirheumatic drugs (primarily hydroxychloroquine). Confirming previous reports, we also observed a possible association between RS3PE and malignancy.