کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3000626 | 1180338 | 2007 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Current Management Strategies for Ovarian Cancer
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کلمات کلیدی
EGFRBSOHNPCCFIGOGOGAUC - AUCICON - آیکونbilateral salpingo-oophorectomy - دو طرفه سالپینو-اووفورکتومیHereditary nonpolyposis colon cancer - سرطان کولون غیرپیپوزی ارثیVascular endothelial growth factor - فاکتور رشد اندوتلیال عروقیVascular Endothelial Growth Factor (VEGF) - فاکتور رشد اندوتلیال عروقی (VEGF)International Federation of Gynecology and Obstetrics - فدراسیون بین المللی زنان و زایمانarea under the curve - منطقه تحت منحنیGynecologic Oncology Group - گروه انکولوژی زنان و زایمانEpidermal growth factor receptor - گیرنده فاکتور رشد اپیدرمال
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Epithelial ovarian cancer originates in the layer of cells that covers the surface of the ovaries. The disease spreads readily throughout the peritoneal cavity and to the lymphatics, often before causing symptoms. Of the cancers unique to women, ovarian cancer has the highest mortality rate. Most women are diagnosed as having advanced stage disease, and efforts to develop new screening approaches for ovarian cancer are a high priority. Optimal treatment of ovarian cancer begins with optimal cytoreductive surgery followed by combination chemotherapy. Ovarian cancer, even in advanced stages, is sensitive to a variety of chemotherapeutics. Although improved chemotherapy has increased 5-year survival rates, overall survival gains have been limited because of our inability to eradicate all disease. Technologic advances that allow us to examine the molecular machinery that drives ovarian cancer cells have helped to identify numerous therapeutic targets within these cells. In this review, we provide an overview of ovarian cancer with particular emphasis on recent advances in operative management and systemic therapies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 82, Issue 6, June 2007, Pages 751-770
Journal: Mayo Clinic Proceedings - Volume 82, Issue 6, June 2007, Pages 751-770
نویسندگان
Giovanni D. MD, Mary M. MD, William A. MD, Aminah MD, Lynn C. MD,