کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3002866 1180752 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of birth weight on spontaneous baroreflex sensitivity in adult life
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Effects of birth weight on spontaneous baroreflex sensitivity in adult life
چکیده انگلیسی

Background and aimSeveral epidemiological studies have suggested a link between low birth weight and coronary heart disease; this may be partly due to the association between low birth weight and conventional risk factors. Among the factors involved in the regulation of cardiovascular homeostasis, baroreflexes play a crucial role. The objective of the present study was to investigate if baroreflex sensitivity (BRS) in adulthood is associated with birth weight.Methods and resultsTwo hundred and eleven adults from Turin, Italy, aged 22–24 years, were examined in a cross sectional survey. Birth weight, blood pressure, pulse rate, family history of hypertension, anthropometric and environmental parameters and spontaneous baroreflex sensitivity were evaluated. In this study we observed a significant increase in baroreflex sensitivity across the tertiles of birth weight, even after correction for gender, blood pressure and heart rate; in a regression model, birth weight was positively and independently associated with BRS; moreover, BRS showed a significant negative correlation with adult pulse rate.ConclusionThis finding may be helpful in understanding the association between low birth weight and cardiovascular disease outcome in later life, since baroreflex failure is associated with an increased cardiovascular morbidity and mortality.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition, Metabolism and Cardiovascular Diseases - Volume 17, Issue 4, May 2007, Pages 303–310
نویسندگان
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