کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3053760 1580027 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Non-traumatic spinal cord ischaemia in childhood – Clinical manifestation, neuroimaging and outcome
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
Non-traumatic spinal cord ischaemia in childhood – Clinical manifestation, neuroimaging and outcome
چکیده انگلیسی

BackgroundSpinal cord ischaemia is rare in childhood and information on clinical presentation and outcome is scarce.MethodsThis is a retrospective analysis of eight patients and 75 additional cases from the literature. Data search included: patient's age, primary manifestation, risk factors, neuroimaging and outcome.ResultsFive female and three male patients gave consent to participate. Mean age was 12.5 years (10–15 years). Six patients presented with paraplegia; this was preceded by pain in four. Brown Sequard syndrome and quadriparesis were the two others' presenting condition. Sensation levels were thoracolumbar in seven cases. Bladder dysfunction only or bladder and bowel dysfunction were reported in eight and five patients respectively. Time to maximal symptom manifestation was <12 h in 7/8. Risk factors included surgery, minor trauma, recent infection, and thrombophilia. Mean follow-up was 3.3 years (0.25–6.3 years). Three patients remained wheelchair-dependent and three patients were ambulatory without aid. Bladder function recovered fully in five children. Most affected aspects of quality of life were physical and mental well-being and self-perception.T2-weighted-MR images showed pencil-like hyperintensity (8/8) in sagittal and H-shaped or snake-eyes-like lesion (6/8) in axial views.Analyses of all 83 patients were in congruence with the above results of the study group.ConclusionSpinal cord ischaemia in childhood presenting with pain, paraplegia, and bladder dysfunction has high morbidity concerning motor problems and quality of life. Acute arterial ischaemic event in children seems similar to adult events with respect to clinical presentation and, surprisingly, also in outcome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Paediatric Neurology - Volume 17, Issue 2, March 2013, Pages 176–184
نویسندگان
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