کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3064062 1580404 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical manifestations and outcomes of the treatment of patients with GABAB encephalitis
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Clinical manifestations and outcomes of the treatment of patients with GABAB encephalitis
چکیده انگلیسی


• FDG-PET showed variable patterns of autoimmune limbic encephalitis.
• Clinical triad of limbic encephalitis, seizure, and association with small-cell lung cancer was identified.
• Comprehensive immunotherapy can be effective.

Encephalitis associated with anti-γ-aminobutyric acid-B (GABAB) receptor antibodies has been identified recently. However, only a few cases have been reported to date and its clinical manifestations and prognosis have not been investigated systematically. We identified five cases of GABAB encephalitis in Korea. Here we present the clinical features, treatment responses, and brain positron emission tomography findings of the cases. The patients had a clinical triad of memory changes, seizure, and association with small-cell lung cancer. Early diagnosis and comprehensive immune modulation may provide a good outcome.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 270, Issues 1–2, 15 May 2014, Pages 45–50
نویسندگان
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