کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3166992 1199337 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications
چکیده انگلیسی

BackgroundOral malignant melanoma must be differentiated from melanotic macule.Study designRetrospective review of 2 series of oral melanotic macule (n = 52) and oral melanoma (n = 130) were conducted to investigate the epidemiology and location involved and assess their differences.ResultsThe mean age of oral melanotic macule patients was 47.3 years, with female:male ratio 2.1 and the lower lip being the predominant location. The mean age of oral melanoma patients was 53.8 years, with no observed sex predilection and the main locations being palate and gingiva. Differences between the 2 cohorts in age (P = .006), gender (P = .014), and lesion site (P < .001) were noted. In this review, 1 case of oral melanotic macule was found to subsequently develop into melanoma.ConclusionsOral melanotic macule may possess malignant potential. Biopsy is recommended to differentiate oral melanoma from melanotic macule for male patients >60 years old with suspected melanotic macule lesion located on the palate.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 112, Issue 1, July 2011, Pages e21–e25
نویسندگان
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