کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3167359 1586350 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Detection of HCV RNA in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Detection of HCV RNA in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C
چکیده انگلیسی

ObjectiveThe objective of this study was to investigate the prevalence of hepatitis C virus (HCV) RNA in saliva and its possible association with xerostomia and hyposalivation in patients with chronic hepatitis C.Study designOne hundred and thirty-six patients with confirmed diagnosis of chronic hepatitis C were prospectively analyzed before HCV treatment. The prevalence of xerostomia and hyposalivation was clinically evaluated. HCV RNA was investigated in saliva samples by qualitative PCR test. Univariate and multivariate analyses were used to verify associations.ResultsXerostomia was reported by 48 (35.3%) patients, whereas hyposalivation was observed in 26 (19.1%). HCV RNA was positive in the saliva of 53 (39.0%) patients. An association among HCV RNA–positive saliva with xerostomia or hyposalivation was not observed.ConclusionOur results demonstrate that the detection of HCV in saliva does not correlate with salivary flow or xerostomia in patients with chronic hepatitis C.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 109, Issue 6, June 2010, Pages 851–856
نویسندگان
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