Sebaceous carcinoma of the oral cavity: a case report and review of the literature

We report the clinical and pathologic features of an intraoral sebaceous carcinoma and review the literature. The intraoral buccal mucosal tumor from a 50-year-old man was a poorly differentiated carcinoma with sebaceous differentiation and expression of androgen receptor. Fordyce granules and a minor salivary gland with a duct were identified in vicinity to the tumor. We discuss the differential diagnosis and histogenesis. The patient underwent surgery and adjuvant radiation therapy.