کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3167640 | 1199375 | 2010 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A histopathologic comparison between synchronous and single primary oral squamous cell carcinomas A histopathologic comparison between synchronous and single primary oral squamous cell carcinomas](/preview/png/3167640.png)
ObjectiveThis study compares synchronous oral squamous cell carcinomas (OSCCs) with single primary OSCCs to assess the histopathologic parameters with a known prognostic significance.Study designTwenty-eight cases of synchronous OSCCs and a control group of single primary OSCCs were compared for 15 histologic prognostic variables.ResultsResults showed significantly less amount of abnormal mitoses (synchronous-1: P = .002; synchronous-2: P = .006) and tumor-induced stroma (synchronous-1: P = .011; synchronous-2: P = .001) in synchronous OSCCs than in single primary OSCCs. Depth of invasion was considerably lower in synchronous OSCCs than in single primary OSCCs (synchronous-1: P = .007; synchronous-2: P = .002). Lymph node metastasis (synchronous-1: P = .051; synchronous-2: P = .051) was found to be rare in synchronous OSCCs compared with single primary OSCCs.ConclusionSynchronous OSCCs show less aggressive histopathologic features than single primary OSCCs.
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 109, Issue 5, May 2010, Pages 732–738