کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3168293 1199403 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bacteria in the apical root canal of teeth with primary apical periodontitis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Bacteria in the apical root canal of teeth with primary apical periodontitis
چکیده انگلیسی

ObjectiveBacteria settled in the apical root canal are in a privileged position to inflict damage to the periradicular tissues. Therefore, the species identified in this region can be of special relevance for the pathogenesis of apical periodontitis. This study investigated the occurrence and levels of several bacterial taxa in the apical root canal of teeth with apical periodontitis.Study designDNA extracts from samples taken from the apical part of the root canal of extracted teeth evincing chronic apical periodontitis lesions served as templates for analysis of the presence and levels of 28 bacterial species/phylotypes using a 16S ribosomal RNA gene–based reverse-capture checkerboard hybridization assay.ResultsBacterial DNA was detected in 19 out of 20 samples. Detected taxa included Pseudoramibacter alactolyticus (32%), Bacteroidetes clone X083 (26%), Streptococcus species (21%), Olsenella uli (10.5%), Synergistes clone BA121 (10.5%), Fusobacterium nucleatum (10.5%), Porphyromonas endodontalis (10.5%), Dialister clone BS016 (5%), Filifactor alocis (5%), Parvimonas micra (5%), and Treponema denticola (5%). Of these, only Bacteroidetes clone X083 and Synergistes clone BA121 were found at levels above 105.ConclusionOccurrence of these bacterial taxa in the apical part of infected root canals indicates their potential pathogenetic role in the etiology of apical periodontitis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 107, Issue 5, May 2009, Pages 721–726
نویسندگان
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