کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3168420 1586353 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Salivary levels of cortisol and chromogranin A in patients with dry mouth compared with age-matched controls
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Salivary levels of cortisol and chromogranin A in patients with dry mouth compared with age-matched controls
چکیده انگلیسی

ObjectiveTo evaluate the salivary levels of cortisol and chromogranin A (CgA) in patients with dry mouth (perceived xerostomia and hyposalivation) compared with age-matched controls.Study designWe studied 174 subjects, including those with dry mouth, classified into 2 subgroups based on perceived xerostomia and salivation, and those without (control subjects). The control subjects were patients at the same hospital and healthy volunteers. Cortisol and CgA levels in stimulated whole saliva were measured using ELISA kits.ResultsAll subjects with dry mouth had significantly higher cortisol and CgA levels than the control subjects. The statistical associations remained significant when they were divided into the 2 subgroups, although somewhat weaker associations were observed. The influences of xerogenic drugs were found to be minimal on salivary flow rate and levels of cortisol and CgA.ConclusionsWe found significant associations between salivary cortisol and CgA levels and symptoms of oral dryness and reduced salivary flow.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 106, Issue 6, December 2008, Pages 833–839
نویسندگان
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