کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3168798 1199435 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Improved treatment of mandibular odontogenic cysts with platelet-rich gel
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Improved treatment of mandibular odontogenic cysts with platelet-rich gel
چکیده انگلیسی

BackgroundPlatelets play a central role in hemostasis and healing processes. By concentrating platelets, platelet-rich plasma (PRP) with higher levels of growth factors can be obtained, which might stimulate healing processes. After platelet degranulation, massive release of growth factors and active substances occurs and gelatinous matrix-platelet-rich gel (PRG) is formed.ObjectiveIn this double-blind study, we report the influence of PRG on healing of mandibular odontogenic cysts.Study designWe examined 23 cases divided into control (no PRG treatment) and experimental (PRG-treated) groups. Each participant was followed on a regular basis with clinical examinations, roentgenograms, and dual-energy x-ray absorptiometry (DEXA) examinations.ResultsClinical observations showed that oral mucosa healed faster in patients treated with PRG compared with cases where gel was not added. Roentgenograms and DEXA examinations showed considerable enhancement of bone regeneration beginning from the 5th week and continuing during subsequent periods after implantation of PRG in the experimental group compared with the control group.ConclusionsIn our opinion, PRG possesses inductive properties that could stimulate the healing processes. The use of autologous growth factors from platelet gel seems to be one of the most promising methods of treatment of bone, cartilage, and soft tissue defects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 105, Issue 4, April 2008, Pages 423–429
نویسندگان
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