کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3169300 | 1199463 | 2007 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Oral leiomyosarcomas: report of two cases with immunohistochemical profile Oral leiomyosarcomas: report of two cases with immunohistochemical profile](/preview/png/3169300.png)
Leiomyosarcoma of the oral cavity is a very rare tumor associated with aggressive clinical behavior and low survival. In this paper, we report 2 cases of leiomyosarcoma, affecting the gingival mucosa of a 54-year-old female and the maxillary bone of a 63-year-old male. Histologically, the tumors were composed of variably oriented fascicles of spindle-shaped cells with cigar-shaped nuclei and eosinophilic cytoplasm. The lesions were treated by surgical resection. Immunoreactivity to anti-vimentin, anti–smooth muscle actin, anti-desmin, anti-laminin, and anti–muscle-specific actin antibodies were found; conversely, the tumor cells were negative for anti-S100 and AE1/AE3 proteins. This report emphasizes the role of immunohistochemical study for correct diagnosis of leiomyosarcoma.
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 104, Issue 4, October 2007, Pages e50–e55