کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3169620 | 1199480 | 2007 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Central giant cell granuloma associated with central ossifying fibroma of the jaws: a clinicopathologic study Central giant cell granuloma associated with central ossifying fibroma of the jaws: a clinicopathologic study](/preview/png/3169620.png)
ObjectiveTo investigate the prevalence of clinical, radiographic, and histopathologic characteristics of combined central giant cell granuloma (CGCG) and central ossifying fibroma (COF).Study designRetrospective clinical and histomorphometric analysis of all cases diagnosed as CGCG or COF between 1994 and 2002.ResultsA total of 51 cases were included in the study: CGCG (n = 23), COF (n = 25), and combined COF-CGCG (n = 3). All 3 lesions presented expansile, well-defined unilocular radiolucencies, with radiopacities (66%), root resorption (66%) and tooth displacement (33%). Microscopically, areas of classical CGCG and COF were separated by a transition zone of nonvascularized densely packed spindle cells. Surgical procedure resulted in recurrence within 1 year in 1 of 2 patients, calcitonin nasal spray treatment resulted in growth arrest in 1 case.ConclusionsBecause of the small number of the combined cases, the biologic behavior of the lesions is uncertain. The CGCG component may drive the clinical behavior toward a more aggressive behavior than classical COF; therefore, close follow-up is recommended.
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 103, Issue 4, April 2007, Pages e35–e41