کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3170014 | 1199501 | 2006 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Clinicopathologic aspects of oral leukoplakia in smokers and nonsmokers Clinicopathologic aspects of oral leukoplakia in smokers and nonsmokers](/preview/png/3170014.png)
ObjectiveThe present study assessed possible clinicopathologic differences between oral leukoplakia in current smokers and never-smokers.Study designRetrospective study of 52 patients with oral leukoplakia. Clinical and pathologic data (age, sex, lesion size, lesion location, and presence/absence of dysplasia) were compared between 41 current-smoking patients and 11 never-smoking patients.ResultsThe mean age of the smoking patients was 49 yrs, significantly lower than the never-smoking patients (59 yrs) (P < .05). The proportion of women was markedly and significantly higher in the never-smoker group than in the smoker group (82% vs. 22%). The odds ratio for lesions on the tongue (0.80, 95% CI 0.01-0.37) was statistically significant at the 5% level (i.e., 95% CI). Dysplastic lesions were observed most frequently in the never-smoking patients, and this difference was statistically significant (P = .026).ConclusionsThe results of the present study indicate that nonsmoking-related oral leukoplakia lesions are more frequent among women than among men, are more likely to be located on the tongue than smoking-related lesions, and show epithelial dysplasia more frequently than smoking-related lesions.
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 102, Issue 2, August 2006, Pages 199–203