کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3170086 1199515 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Psammomatoid ossifying fibromas: Immunohistochemical analysis and differential diagnosis with psammomatous meningiomas of craniofacial bones
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Psammomatoid ossifying fibromas: Immunohistochemical analysis and differential diagnosis with psammomatous meningiomas of craniofacial bones
چکیده انگلیسی

ObjectiveTo clarify the role of immunohistochemistry in the diagnosis of psammomatoid ossifying fibroma (PSOF), conventional cemento-ossifying fibroma (COF), and psammomatous meningioma (PM) of the craniofacial skeleton.Study designThe histology and immunohistochemistry of 4 PSOFs, 6 COFs, and 7 PMs was studied. Antibodies included EMA, cytokeratins, smooth muscle actin (SMA), desmin, vimentin, CD34, CD10, S-100 protein, and glial fibrillary acidic protein (GFAP).ResultsAll PSOFs showed multiple round ossicles homogeneously distributed within a fibroblastic stroma. Psammomatous meningiomas had meningothelial features. All tumors, except 1 COF, were positive for EMA. All of them expressed vimentin, and none showed cytokeratins. Staining for SMA and S-100 protein was variable. CD10 was positive in all cases except 2 meningiomas. CD34 and GFAP stained only 1 case of meningioma each.ConclusionsThe diagnosis of PSOF should rest on histologic features. An incorrect diagnosis of meningioma based on the expression of EMA should be avoided.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 101, Issue 5, May 2006, Pages 614–619
نویسندگان
, , , , ,