کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3170118 1199516 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acceleration of de novo bone formation following application of autogenous bone to particulated anorganic bovine material in vivo
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Acceleration of de novo bone formation following application of autogenous bone to particulated anorganic bovine material in vivo
چکیده انگلیسی

ObjectiveThis prospective animal study examined the de novo bone formation following application of deproteinized bovine bone matrix (DBBM) with or without autogenous bone (AB) to osseous defects.Study designDefects of defined size were created in the frontal skull of domestic pigs and filled with DBBM alone (group A) and DBBM+25%AB (group B). De novo bone formation was analyzed qualitatively and quantitatively at 9 different times (0.5, 1, 2, 3, 4, 6, 8, 12, 26 weeks) by means of light microscopy, microradiography, and statistical analysis.ResultsHistological analysis indicated sufficient osseointegration of DBBM in both groups. Microradiography demonstrated a significant increase of bone formation in group B after 6 weeks (P = .0159) and 8 weeks (P = .0317).ConclusionThe addition of 25%AB to DBBM results in accelerated de novo bone formation in osseous defects. This effect is likely caused by osteoinductive properties of cellular elements transplanted with the autogenous bone.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 101, Issue 3, March 2006, Pages 309–316
نویسندگان
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