کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
322992 540305 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mammalian animal models of psychosexual differentiation: When is ‘translation’ to the human situation possible?
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Mammalian animal models of psychosexual differentiation: When is ‘translation’ to the human situation possible?
چکیده انگلیسی

Clinical investigators have been forced primarily to use experiments of nature (e.g., cloacal exstrophy; androgen insensitivity, congenital adrenal hyperplasia) to assess the contribution of fetal sex hormone exposure to the development of male- and female-typical profiles of gender identity and role behavior as well as sexual orientation. In this review, I summarize the results of numerous correlative as well as mechanistic animal experiments that shed significant light on general neuroendocrine mechanisms controlling the differentiation of neural circuits controlling sexual partner preference (sexual orientation) in mammalian species including man. I also argue, however, that results of animal studies can, at best, provide only indirect insights into the neuroendocrine determinants of human gender identity and role behaviors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hormones and Behavior - Volume 50, Issue 4, November 2006, Pages 579–588
نویسندگان
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