The History of Sepsis Management Over the Last 30 Years

Sepsis and septic shock remain one of the leading causes of morbidity and mortality in children. Collaboration of clinicians and researchers in the fields of infectious diseases, basic science, genetics, genomics, and critical care has resulted in significant progress in understanding the pathophysiology, advances in prevention, early identification of patients at risk, and the development of coordinated therapies, resulting in improved outcomes.