Indicaciones de la anticoagulación en pacientes con diabetes

Cardiovascular diseases are the main cause of death in diabetic patients. Besides the classic atherogenic and atherothrombotic risk factors, other specific factors of diabetes should be added as endothelial dysfunction, alteration of hemostatic processes and diabetic dyslipidemia. Laboratory results indicate the existence of a hypercoagulable state with increase of the platelet function, alteration of the plasmatic coagulation and decreases in natural inhibitors. This situation facilitates the appearance of thrombosis, underlying the importance of the preventive antithrombotic therapy in these patients. The indication of anticoagulant therapy should be individualized for every patient according to the etiopathogenesis of the absolute thromboembolic risk and/or of the interventional procedure to be performed, if it is necessary.