کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3254464 | 1207204 | 2009 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Non-NSAID non-H. pylori ulcer disease Non-NSAID non-H. pylori ulcer disease](/preview/png/3254464.png)
Non-NSAID non-Helicobacter pylori ulcer disease, which was believed to account for a minority of bleeding gastroduodenal ulcers, has been increasingly recognized for the past decade. Current data suggest that both relative proportion and actual numbers of patients with non-NSAID non-H. pylori ulcers have increased, whereas the prevalence of H. pylori-positive ulcers has declined. There is evidence to support that non-NSAID non-H. pylori ulcers associate with a higher risk of recurrent ulcer bleeding and a higher overall mortality as compared to H. pylori-positive ulcer disease. Patients with non-NSAID non-H. pylori ulcers are often older, sicker and more frequently experience bleeding episodes while in hospital. The pathogenesis of non-NSAID non-H. pylori ulcer is largely unknown and the efficacy of acid suppressants in the management and prevention of the disease remains to be defined. Well-designed, large-scale studies are awaited to shed light on this emerging condition.
Journal: Best Practice & Research Clinical Gastroenterology - Volume 23, Issue 1, February 2009, Pages 3–9