Emerging infections of the gastrointestinal tract

Infections account for significant GI morbidity and mortality worldwide. New organisms are being identified, associated with diarrhoeal illness and some with other gastrointestinal illness as well. Among GI viruses, Sapovirus is now recognised to cause diarrhoea, especially in children. A hypervirulent strain of Clostridium difficile has caused epidemics in many countries. Newly identified bacterial species that may cause diarrhoea include Campylobacter concisus, Arcobacteria, Edwardsiella tarda, Aeromonas, Plesiomonas and Laribacter. Helicobacteria are reviewed, as well as the role of gastric acid suppression in predisposing to enteric infections.