کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3254506 1207207 2007 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The patient with recurrent (sub) obstruction due to Crohn's disease
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
The patient with recurrent (sub) obstruction due to Crohn's disease
چکیده انگلیسی

Stricturing Crohn's disease (CD) occurs in 12–54% of the CD patient population and is associated with significant morbidity and impaired quality of life.The detailed pathophysiology of stricture formation has not been fully elucidated, but is primarily associated with luminal narrowing secondary to inflammation and the fibrosis that ensues during mucosal healing. The diagnosis of stricturing disease is based on clinical signs and symptoms along with imaging modalities. The advantages and shortcomings of each imaging modality are discussed.Treatment options are based on the differentiation between inflammatory versus fibrous-predominant strictures; whereas the former can potentially be managed with conservative medical treatment, the latter necessitates a mechanical solution through endoscopy or surgery. Indications, contra-indications and success rates of the different therapeutic approaches are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Gastroenterology - Volume 21, Issue 3, June 2007, Pages 427–444
نویسندگان
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