کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3267999 | 1589549 | 2009 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Genetics of Type 1 Diabetes and Autoimmune Thyroid Disease
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The search for the susceptibility alleles for the complex genetic conditions of type 1 diabetes and autoimmune thyroid diseases has gained momentum in recent years. Studies have revealed several novel disease susceptibility alleles of relevance to both conditions, which brings the total number of genetic variants contributing to type 1 diabetes to ten. Additional genetic loci remain to be discovered, particularly in the autoimmune thyroid diseases. In the future, the density and coverage of single nucleotide polymorphisms available for high throughput genotyping will improve, and detailed analysis of the role of copy number variants in these diseases will shed new light on the pathogenesis of these common endocrinopathies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Endocrinology and Metabolism Clinics of North America - Volume 38, Issue 2, June 2009, Pages 289-301
Journal: Endocrinology and Metabolism Clinics of North America - Volume 38, Issue 2, June 2009, Pages 289-301
نویسندگان
Simon H.S. MD, Tony R. PhD,