کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3268067 | 1589544 | 2010 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Toward Closing the Loop: An Update on Insulin Pumps and Continuous Glucose Monitoring Systems
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
غدد درون ریز، دیابت و متابولیسم
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چکیده انگلیسی
This article reviews current pump and continuous glucose monitoring therapy and what will be required to integrate these systems into closed-loop control. Issues with sensor accuracy, lag time, and calibration are discussed as well as issues with insulin pharmacodynamics, which result in a delayed onset of insulin action in a closed-loop system. A stepwise approach to closed-loop therapy is anticipated, where the first systems will suspend insulin delivery based on actual or predicted hypoglycemia. Subsequent systems may control to range, limiting the time spent in hyperglycemia by mitigating the effects of a missed food bolus or underestimate of consumed carbohydrates, while minimizing the risk of hypoglycemia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Endocrinology and Metabolism Clinics of North America - Volume 39, Issue 3, September 2010, Pages 609-624
Journal: Endocrinology and Metabolism Clinics of North America - Volume 39, Issue 3, September 2010, Pages 609-624
نویسندگان
Tandy MD, Jen RN, CDE, Bruce MD,