کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3268088 1589552 2008 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Adipocyte as an Endocrine Cell
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
The Adipocyte as an Endocrine Cell
چکیده انگلیسی

Adipose tissue contains many cell types. Among the more abundant are adipocytes, preadipocytes, immune cells, and endothelial cells. During times of excess caloric intake, these cells have to adjust and remodel to accommodate the increased demand for triglyceride storage. Based on a comprehensive analysis of the total adipose tissue secretome, this article focuses on three areas of adipokine biology: (1) How does the adipocyte interact with the extracellular matrix over the course of obestiy? (2) Does the adipocyte, per se, play a role in the innate immune response? (3) How is the angiogenic profile of adipose tissue linked to the development of insulin resistance? The authors present a comprehensive overview of all of the currently available secreted adipose tissue products that have been identified at the protein level.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Endocrinology and Metabolism Clinics of North America - Volume 37, Issue 3, September 2008, Pages 753–768
نویسندگان
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