کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3272650 1208349 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunité innée et adaptative du tractus génital féminin
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Immunité innée et adaptative du tractus génital féminin
چکیده انگلیسی
Most of molecules and cells involved in both types, innate and adaptive immunity are present within the feminine genital tract. This article attempts to list some of the various actors involved in these immunities, essentially at the vaginal level and to illustrate their implications in the most frequent pathologies. Among these molecules: defensins, collectins lysozyme, lactoferrin, calprotectin, SLP1, HSP and many others as well as Toll receptors and immunoglobulins (IgG and IgA) play a major role. Epithelial cells, antigen presenting cells, lymphocytes T, B, NK also contribute efficiently to the defenses in a coordinated way partially under the influence of sex hormones. The therapeutic perspectives, of which vaccines are briefly mentioned.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal de Gynécologie Obstétrique et Biologie de la Reproduction - Volume 41, Issue 7, November 2012, Pages 612-622
نویسندگان
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