کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3273728 1208413 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Risque de cancer du sein lié à la grossesse
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Risque de cancer du sein lié à la grossesse
چکیده انگلیسی
After a pregnancy, there is a transitory increase in the risk of breast cancer. During the pregnancy, the number of mammary epithelial cells increases massively. This increase seems partly due to the expansion of stem cells and proliferating intermediate cells. This proliferation of epithelial cells is accompanied by angiogenesis and by recruitment of stromal cells, as well as changes of the extracellular matrix. During any pregnancy, there is cell trafficking between mother and foetus. Hematopoietic or mesenchymal foetal stem cells are transferred in maternal circulation and could be used by the tumor as support cells and take part in the tumoral development. The study of the mechanisms of this specific oncogenesis may help to develop chemoprevention strategies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal de Gynécologie Obstétrique et Biologie de la Reproduction - Volume 37, Issue 1, February 2008, Pages 77-81
نویسندگان
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