کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3276543 1208575 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cachexia assessed by bioimpedance vector analysis as a prognostic indicator in chronic stable heart failure patients
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Cachexia assessed by bioimpedance vector analysis as a prognostic indicator in chronic stable heart failure patients
چکیده انگلیسی

BackgroundThis study explored whether the cachectic state assessed by bioimpedance vector analysis provides additional prognostic information about mortality from all causes.MethodsWe included 519 consecutive patients with stable chronic heart failure (mean age 62.5 ± 16.4 y; 286 males). Cachexia was identified in those subjects who fell outside the right lower quadrant of the reference curve of 95% on the resistance/reactance graph [bioelectrical impedance vectorial analysis (BIVA)-cachexia]. Clinical, anthropometric, and biochemical data were also evaluated.ResultsPatients with BIVA-cachexia (n = 196, 37.8%) were older and had significantly lower ejection fraction, handgrip strength, serum albumin, total cholesterol, and triglycerides. The frequency of patients with body mass index < 20, decreased muscle strength, hypoalbuminemia, anemia, anorexia, New York Heart Association functional classes III/IV and edema, as well as creatinine levels, resistance/height, and impedance index was significantly higher in the cachexia group. During 29 ± 11 mo of follow-up, 39 (19.9%) patients with BIVA-cachexia and 38 (11.7%) patients without BIVA-cachexia (P < 0.0001) died.ConclusionsThe cachectic state is an independent risk factor for mortality in chronic heart failure patients. BIVA could represent a valuable tool to assess presence of cachexia as changes in body cell mass in heart failure patients because provide information additional to weight loss.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 28, Issue 9, September 2012, Pages 886–891
نویسندگان
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