کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3277325 1208612 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of milk tripeptides on blood pressure: A meta-analysis of randomized controlled trials
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Effect of milk tripeptides on blood pressure: A meta-analysis of randomized controlled trials
چکیده انگلیسی

ObjectiveTo better understand and summarize the relation between milk peptide intake and blood pressure (BP), we conducted a meta-analysis of randomized controlled trials to assess the effects of the milk-derived tripeptides isoleucine-proline-proline and valine-proline-proline on BP in prehypertensive and hypertensive subjects.MethodsNine studies including 12 trials published between 1996 and 2005 with a total of 623 participants were included. Two researchers independently extracted data from the original publications. A fixed-effects model was used for meta-analysis because of the homogeneity among trials.ResultsSignificant decreases of 4.8 mmHg (95% confidence interval 3.7–6.0) in systolic BP and 2.2 mmHg (95% confidence interval 1.3–3.1) in diastolic BP were found after the pooling of these trials. When trials were separated by BP status, hypotensive effects appeared to be larger in hypertensive subjects than in prehypertensive subjects. As a trend, the hypotensive effects became more obvious as the intervention lengthened.ConclusionOur analysis provided evidence that milk-derived tripeptides have hypotensive effects in prehypertensive and hypertensive subjects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 24, Issue 10, October 2008, Pages 933–940
نویسندگان
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