کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
332576 545733 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sleep onset REM periods in obsessive compulsive disorder
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Sleep onset REM periods in obsessive compulsive disorder
چکیده انگلیسی

Sleep studies in patients with obsessive compulsive disorder (OCD) are sparse and results inconsistent. Moreover, in 3 out of 4 published studies up to 50% of patients suffered from secondary major depression. In this study, 10 inpatients with a DSM-IV diagnosis of OCD without comorbid major depression (Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score > 15; Hamilton Depression Rating Scale (HAMD)-21 total score < 17) and 10 healthy matched controls were included. Polysomnography of patients (7 males, 3 females, 34.5 ± 12.7 years, Y-BOCS: 27.8 ± 4.6, HAMD-21: 13.3 ± 1.9) and controls (7 males, 3 females, 34.4 ± 12.8 years) was recorded, following an adaptation night. Sleep variables did not significantly differ in both groups except that stage 4 sleep was reduced in patients. Three of the patients with OCD, however, exhibited sleep onset REM periods (SOREMPs), i.e. rapid-eye-movement (REM) latencies < 10 min. Obsessive compulsive symptoms were significantly (P < 0.05) more severe in these patients (Y-BOCS: 32 ± 2.0) compared to those without SOREMPs (Y-BOCS 26 ± 4.2). This is, to our knowledge, the first report of sleep onset REM periods in OCD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 152, Issue 1, 30 July 2007, Pages 29–35
نویسندگان
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