Study comparing lipid metabolism disorders and effectiveness of treatment in HIV infected patients on long-term treatment with various thymidine analogues

Disorders in lipid metabolism exist in most patients treated for the long time. In our study were included 186 patients on antiretroviral treatment lasting 96 weeks treated either with AZT/3TC or with D4T/3TC. Performed studies have shown that both d4T/3TC and AZT/3TC regimens are effective as backbone of CART. Similar immunological values are achieved using above mentioned regimens. Elevation of TG and TC level during antiretroviral therapy is much more frequent in persons treated with d4T/3TC and is not dependent on type of the third drug used.