Pharmacogenetics in HIV Clinical Practice

The best choosing of antiretroviral therapy for an individual patient is one that physicians have always tried to practice, making use of whatever knowledge or tools are available to guide treatment decisions. Individual genetic variations provide scope for a wide range of host-drug interactions that will differentiate therapeutic outcomes within an otherwise homogenous population. Pharmacogenetics looks set to become an increasingly important field to refine the medical tools to personalize antiretroviral treatment. The integration of pharmacogenetic tests into routine patient management has a great challenge for HIV - guidelines and for clinical care. Pharmacogenetics will increasingly impact on medical disciplines. The use of genetic tests in clinical practice improve drug prescribing holds great promise to improve the lives of individuals affected by HIV.