Assessment of metformin therapy effect on selected parameters of glucose and lipid metabolism and the course of lipodystrophy in HIV-1 infected patients receiving protease inhibitors - pilot study

1. Metformin is not a useful drug in the therapy of metabolic abnormalities (glucose and lipids) due to protease inhibitors; 2. Metformin influences adipose tissue redistribution and thus can be recommended in the treatment of HIV-1 infected patients with lipodystrophy, to improve adherence and quality of life.