کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3334332 | 1213437 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Testing for Hereditary Predisposition in Patients with Gynecologic Cancers, Quo Vadis?
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
هماتولوژی
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چکیده انگلیسی
Genetic testing for a hereditary predisposition to gynecologic cancers has been available clinically since the 1990s. Since then, knowledge of the hereditary contribution to gynecologic cancers has dramatically increased, especially with respect to ovarian cancer. Although knowledge of the number of gynecologic cancer-predisposing genes has increased, the integration of genetic predisposition testing into routine clinical practice has been much slower. This article summarizes the technical and practical aspects of genetic testing in gynecologic cancers, the potential barriers to more widespread access and practice of genetic testing for hereditary predisposition to gynecologic cancers, and the potential solutions to these barriers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Pathology Clinics - Volume 9, Issue 2, June 2016, Pages 301-306
Journal: Surgical Pathology Clinics - Volume 9, Issue 2, June 2016, Pages 301-306
نویسندگان
Gillian MBBS, RCPSC, PhD, Kasmintan A. MBBS, FRCPC, PhD,