کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3334333 1213437 2016 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prophylactic Gynecologic Specimens from Hereditary Cancer Carriers
ترجمه فارسی عنوان
نمونه های پیشگیرانه غدد جنسی از حاملان سرطانی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
چکیده انگلیسی

Hereditary breast ovarian cancer and Lynch/hereditary nonpolyposis colorectal cancer syndrome account for most hereditary gynecologic cancers. In the absence of effective cancer screening and other preventative strategies, risk-reducing surgery in women who are known to be at genetic risk of BRCA-associated or of Lynch syndrome carcinomas is effective in significantly decreasing the lifetime risk of developing malignancy. Reflex genomic testing of high-grade ovarian cancers and reflex immunohistochemistry in endometrial cancers will lead to greater recognition of germline-associated cancers. Approaches to processing surgical specimens, the recognition and classification of cancer precursor lesions, and differentiation from their mimics are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Pathology Clinics - Volume 9, Issue 2, June 2016, Pages 307–328
نویسندگان
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