کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3334444 1213443 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing Biological Aggression in Adrenocortical Neoplasia
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Assessing Biological Aggression in Adrenocortical Neoplasia
چکیده انگلیسی

Pathologists are highly skilled at the evaluation of adrenal neoplasms. Occasional adrenocortical tumors can be diagnostically challenging and supplementary tools can assist in these cases. Histologic and molecular studies support a model that includes 2 broad classes of adrenocortical carcinoma with distinct somatic genetic alterations and clinical outcomes. Pathologists should endeavor to grade adrenocortical carcinomas to assign each case into one of these 2 classes. Mitotic grading by mitotic counting and Ki-67 immunohistochemistry represent the most practicable and informative methods currently available.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgical Pathology Clinics - Volume 7, Issue 4, December 2014, Pages 533–541
نویسندگان
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