کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3341434 | 1214211 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Vitiligo: Pathogenesis, clinical variants and treatment approaches
ترجمه فارسی عنوان
ویتیلیگو: پاتوژنز، انواع بالینی و روشهای درمان
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Vitiligo is a common chronic acquired disease of pigmentation whose etiology is unknown, which usually occurs with asymptomatic whitish patch or macule. Although several hypotheses have been proposed in the literature, the leading theory is still the auto-immune etiology linked to specific genetic mutations. Vitiligo can also be associated with several autoimmune diseases, including autoimmune thyroid diseases, alopecia areata, and halo nevi.Sensorineural hearing loss was reported in several vitiligo patients due to a reduction in the number of melanocytes contained in the membranous labyrinth of the inner ear. Because of its complexity, several therapeutic options are available to treat this systemic disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 15, Issue 4, April 2016, Pages 335–343
Journal: Autoimmunity Reviews - Volume 15, Issue 4, April 2016, Pages 335–343
نویسندگان
Giannicola Iannella, Antonio Greco, Dario Didona, Biagio Didona, Guido Granata, Alessandra Manno, Benedetta Pasquariello, Giuseppe Magliulo,