کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3341830 | 1214245 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immune regulatory mechanisms in ANCA-associated vasculitides
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Immune regulatory mechanisms in ANCA-associated vasculitides Immune regulatory mechanisms in ANCA-associated vasculitides](/preview/png/3341830.png)
چکیده انگلیسی
A group of primary vasculitides is associated with the presence of anti-neutrophil cytoplasmic autoantibodies (ANCA). In these diseases, the contribution of ANCA to disease pathogenesis has been studied extensively. Also, in patients with ANCA-associated vasculitides, the T lymphocyte compartment is dysregulated, as aberrant distribution and function of T cell subsets has been shown. In this review we will discuss the putative role of T lymphocytes in inflammation and granuloma formation, as well as the involvement of B cell compartments in the pathophysiology of ANCA-associated vasculitis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 11, Issue 2, December 2011, Pages 77–83
Journal: Autoimmunity Reviews - Volume 11, Issue 2, December 2011, Pages 77–83
نویسندگان
Nikola Lepse, Wayel H. Abdulahad, Cees G.M. Kallenberg, Peter Heeringa,