کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3341865 1214247 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Treatment of ANCA-associated vasculitides (AAV)
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Treatment of ANCA-associated vasculitides (AAV)
چکیده انگلیسی

Treatment of AAV follows the principle of a combined remission induction and maintenance strategy and is adapted in a stage and activity-adapted fashion. So far the combination therapy of glucocorticoids and conventional immunosuppressive drugs has mainly been used to control disease. This approach has led to a significant improvement in outcome in spite of persistently high early mortality rates of nearly 11% within the first year. Besides conventional treatment, biologics have emerged as a new treatment option. The paper summarizes the current evidence for the use of conventional therapy and biologics in AAV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 12, Issue 4, February 2013, Pages 483–486
نویسندگان
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