کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3342400 1214284 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Granulocyte/monocyte apheresis as immunotherapic tool: Cellular adsorption and immune modulation
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Granulocyte/monocyte apheresis as immunotherapic tool: Cellular adsorption and immune modulation
چکیده انگلیسی

Cellular apheresis is now established as a rational therapeutic procedure in certain inflammatory and autoimmune diseases, particularly in inflammatory bowel diseases, but the efficacy of this procedure can not be fully explained solely on the basis of removal of granulocytes and monocytes. It is suggested that a selective modulator increase of regulatory T cells contributes to beneficial effect of adsorptive leukocytapheresis in patients with these pathologies. Though currently applied as second-line medication, it could be considered in the future as an effective alternative to the use of immune suppressive regimens or biological agents and taken into account to establish a tailor's patient therapy in inflammatory and autoimmune conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 8, Issue 4, February 2009, Pages 292–296
نویسندگان
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