کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3342478 1214288 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Type II collagen autoimmunity in a mouse model of human rheumatoid arthritis
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Type II collagen autoimmunity in a mouse model of human rheumatoid arthritis
چکیده انگلیسی

Type II collagen (CII) is expressed exclusively in the joint articular. Although the relationship between anti-CII immunity and human rheumatoid arthritis (RA) has been studied for a long time, definitive conclusions have not been reached. CII, as an autoantigen, has been studied extensively in small animal models, such as mice, and the collagen-induced arthritis (CIA) model has increased our understanding of the pathogenesis of human RA. In the present report, we summarize the available information on anti-CII immunity and discuss recent updates regarding pathogenesis in the CIA model, including the role of Th17 cells.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 7, Issue 1, November 2007, Pages 65–70
نویسندگان
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