کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3342561 1214293 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The pathogenetic role of HLA-B27 and its subtypes
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
The pathogenetic role of HLA-B27 and its subtypes
چکیده انگلیسی

The strong association between HLA-B27 and ankylosing spondylitis has been known for more than 33 years, but the enigma of the pathogenetic role of the gene and its product has not yet been solved. Ongoing studies have produced evidence supporting different theories to explain this association, and structural and functional studies of HLA-B27 allele products at molecular level have provided information of broad and multidisciplinary value and disclosed new avenues leading to autoimmunity and immune disregulation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 6, Issue 3, January 2007, Pages 183–189
نویسندگان
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