کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3342632 | 1214298 | 2006 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome](/preview/png/3342632.png)
It is well known that antiphospholipid syndrome (APS) is associated with recurrent pregnancies losses, but is also associated with other obstetric features such as preeclampsia, uteroplacental insufficiency and preterm birth. Pregnancy is a hypercoagulable state than can be complicated by thrombosis, especially in those patients with an underlying thrombophilic disorder. Catastrophic APS is a rare form of presentation of the APS. Several trigger factors have been related with the catastrophic APS, including infections, anticoagulation withdrawal, surgery, neoplasms and lupus “flares”. In around 6% of the cases, the catastrophic APS can appear during pregnancy or puerperium. We review this specific subset of the catastrophic APS and propose a therapeutical approach for this particular situation.
Journal: Autoimmunity Reviews - Volume 6, Issue 2, December 2006, Pages 85–88