Correlation between vancomycin and daptomycin MIC values for methicillin-susceptible and methicillin-resistant Staphylococcus aureus by 3 testing methodologies

We examined the potential correlation between vancomycin and daptomycin MIC for 298 Staphylococcus aureus by broth microdilution (BMD), Etest, and MicroScan®. Etest and BMD identified a significant, albeit poor, correlation between MICs (ρ = 0.29, P < .01, and ρ = 0.15, P = .01, respectively), but no correlation (ρ = 0.08, P = .18) was observed with MicroScan.