Prefrontal cortex dysfunction during cognitive tests evidenced by functional near-infrared spectroscopy

Prefrontal cortex oxygenation changes in response to a verbal fluency task and a visual spatial working memory task were investigated by functional near-infrared spectroscopy (fNIRS) on nine patients with schizophrenia. Four patients were reactive to both tests; five reactive to only one of the two tests, suggesting the importance of reporting fNIRS results for each individual.