کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3363223 | 1592145 | 2008 | 7 صفحه PDF | دانلود رایگان |
SummaryObjectivesTo determine: (1) the incidence of invasive salmonellosis, (2) the distribution of specific Salmonella serotypes associated with invasive disease, and (3) the role of demographic characteristics in invasive salmonellosis in Michigan.DesignWe conducted a cross-sectional study using laboratory-confirmed cases of salmonellosis reported to the Michigan Department of Community Health between 1995 and 2001.MethodsAverage annual incidences (AAIs) for invasive salmonellosis were computed, and Poisson regression analysis was used to model the association between demographic attributes and invasive salmonellosis.ResultsOf 6797 cases of salmonellosis, 347 (5.1%) were characterized as invasive having an AAI of 0.5/100 000. A covariate-adjusted Poisson model showed children aged <1 year to be at higher risk for invasive salmonellosis compared to adults aged 40–49 years (rate ratio (RR) 8.98, 95% confidence interval (CI) 5.69–14.17). No significant differences were found between males and females (RR 1.02, 95% CI 0.83–1.26), African-Americans and Caucasians (RR 0.95, 95% CI 0.64–1.42), and urban and rural residents (RR 0.98, 95% CI 0.76-1.26). Among the most common serotypes associated with invasive salmonellosis (Heidelberg, Typhimurium, and Enteritidis), Salmonella serotype Heidelberg had the highest blood invasiveness ratio (15.79/100).ConclusionsChildren aged <1 year, especially of minority groups, are at higher risk for invasive Salmonella infections. Invasive salmonellosis may be included in the differential diagnosis of acute bacterial infections in young children with positive stool cultures for Salmonella.
Journal: International Journal of Infectious Diseases - Volume 12, Issue 2, March 2008, Pages 176–182